Microbial Degradation of Heterocycles- A Review


  • L. H. S. Martins Federal Rural University of Amazonia (UFRA)
  • J. R. Barbosa Federal University of Pará (UFPA)
  • S. B. Silva University of Pará (UFPA)
  • P. W. P. Gomes Federal University of Pará
  • A. Komesu Federal University of São Paulo (UNIFESP)
  • G. V. S. Pereira Federal University of Pará (UFPA)
  • R. C. B. Alves Federal Rural University of Amazonia (UFRA)
  • C. M. G. Bichara Federal Rural University of Amazonia (UFRA)




Biotechnology, Environment pollution, Organic chemistry


Heterocycles are organic compounds that are well-known and distributed in nature; they can be used in the pharmaceutical, agrochemical, and chemical industries. Heterocycles composed of sulfur, nitrogen, and oxygen atoms are harmful toxins and can cause cancers; these substances can persist for years in the environment. One attractive alternative to expensive physical and chemical methods is microbial degradations, which present high potential and low cost, causing minimal environmental impacts. The use of these microorganisms makes use of heterocyclic substances as substrates, removing them efficiently and safely. Some strains of wild and genetically modified microorganisms (bacteria and fungi) have already been used to degrade various pesticides and aromatic compounds. Understanding the biodegradation mechanism of microorganisms will benefit future bioremediation studies, which may prove to be one of the alternatives to solving environmental problems. This review will focus on the microbial degradation of heterocyclic compounds, taking into account the most used techniques and their limitations in future research


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How to Cite

da Silva Martins, L. H. ., Rodrigues Barbosa, J. ., Baleixo da Silva, S. ., Portal Gomes, P. W. ., Komesu, A. ., Vasconcelos da Silva Pereira, G. ., … Goltara Bichara, C. M. . (2023). Microbial Degradation of Heterocycles- A Review. Journal of Science & Sustainable Engineering , 1(1). https://doi.org/10.34024/jsse.2023.v1.15462
Received 2023-08-01
Accepted 2023-08-01
Published 2023-08-03

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